Mounjaro Constipation: What Do You Need to Know?

Blue figure on toilet

If you’re anything at all like me, navigating the complex world of weight loss can feel like a full-time job. With so many options, from diet plans to exercise routines and even medications, it’s easy to get overwhelmed. For many years, weight loss has consumed me, and I have struggled to find something that fits. I recently wrote about the weight loss drug Mounjaro, which is reported to help people who have struggled with weight loss in the past. In that post, I went into detail about what it is and how it works in weight loss. Today, I wanted to touch on a common complaint users have reported: Mounjaro constipation. If you’ve been asking yourself, “Does Mounjaro cause constipation?” or are just curious about its side effects in general, then this post is for you!

As always, before undertaking any kind of weight loss or lifestyle change, it is always best to speak to a medical professional or registered dietician who is best suited to give personalised advice on your individual health needs and health issues. This blog post has been researched to the best of my ability, and the information posted is accurate at the time of publication. With things like this, there are always new developments and advice. It is always best to double-check that any information is accurate and up to date before taking any action. While this post is meant to be informative, it does not replace professional medical advice. 

Astronaut on toilet. Mounjaro constipation

What is Mounjaro? Understanding the Basics

First, let’s recap the basics of the drug Mounjaro and what exactly it is. Mounjaro has the active ingredient tirzepatide, which belongs to a class of drugs known as GLP-1 receptor agonists (Glucagon-Like Peptide-1). Essentially, these drugs work by mimicking a hormone in your body that helps regulate blood sugar levels and appetite, which is why they are commonly used in treating diabetes mellitus and now obesity. Mounjaro has been praised for its effectiveness in aiding weight loss by reducing appetite and controlling blood sugar. You may have heard reports in the news of its popularity amongst celebrities such as Whoopi Goldberg. However, like any medication, it comes with a list of potential side effects that are reported – one of which is constipation.

Does Mounjaro Cause Constipation? Let’s Explore

Now, let’s address the question that’s likely on your mind: Does Mounjaro cause constipation? This answer isn’t black and white and depends on a number of different factors. While Mounjaro is certainly associated with a range of side effects, gastrointestinal issues, including constipation, are among the most common side effects of Mounjaro. This isn’t really all that surprising; considering how the drug interacts with the digestive system, it makes sense that a large proportion of reported side effects are related to this.

Many of us on a weight loss journey have experienced the uncomfortable side effects that some medications can bring, and constipation is often at the top of that list. It’s important to note that the severity of constipation can vary from person to person. For some, it may be a mild inconvenience, while for others, it can lead to more severe complications, such as intestinal blockage or stomach paralysis. That’s why Mounjaro should only ever be taken under the supervision of a trained medical professional. Although constipation is a common side effect, correct monitoring of this needs to be in place to prevent it from turning into something more serious.

Outdoor wooden toilet

Are You Experiencing Mounjaro Constipation?

So, you’ve just started your Mounjaro journeyand you’re hopeful and excited. You’re ready to start seeing results! However, a few days in, you notice a shift. You begin to feel bloated and sluggish, and there’s a heaviness in your stomach that wasn’t there before. You realise you haven’t had a bowel movement in days. Well, this is what Mounjaro constipation can feel like for many people—an uncomfortable, bloated feeling that just won’t go away. 

Understanding the Science Behind Mounjaro Constipation

So, why does Mounjaro cause constipation? The mechanism behind this side effect is largely due to how GLP-1 receptor agonists like tirzepatide function. These drugs slow gastric emptying, which means they slow down how quickly food moves through your digestive tract. The positive of this is that it can lead to feelings of fullness and reduced appetite, which is a benefit for those trying to lose weight. Unfortunately, it can also lead to constipation as a result!

In clinical studies and clinical trials, constipation has been reported as a possible side effect of Mounjaro, along with other gastrointestinal issues like nausea and diarrhoea. The good news is that for most people, these side effects tend to be mild and manageable with some adjustments to diet and lifestyle. How Mounjaro will affect you really depends on how your own body reacts. There is no real way of knowing how impactful these side effects will be from person to person before taking them.

Person holding stomach possible bloating from Mounjaro constipation

Managing Constipation: Tips and Tricks

If Mounjaro constipation is a side effect you experience, there are a few things you can do that may help ease things. Ultimately managing constipation is all about balance. 

Here are some tips that may help:

Stay Hydrated

Make sure you drink plenty of water throughout the day. Staying hydrated can help keep things moving smoothly in your digestive tract.

Eat A Fibre-Rich Diet

Incorporate more fibre into your diet. Eating fruits, vegetables, whole grains, and legumes can help aid digestion and prevent constipation in the long term.

A fruit market stall

Take Part In Physical Activity

Regular physical activity can help stimulate bowel movements. Even something as simple as a daily walk can make a difference. Try to engage in some kind of physical activity every day if you can.

Consult Your Healthcare Provider

Make sure you always discuss any side effects you’re experiencing with your healthcare provider. They might suggest adjusting your dose or trying a different medication altogether. Disclosing this information can make sure they continue to monitor things and that Mounjaro is suitable for you going forward. 

When to Seek Medical Attention

While mild constipation is common and can often be managed with diet and lifestyle changes, it’s crucial to recognise when it is appropriate to seek medical attention. If you start to experience severe symptoms such as severe abdominal pain, severe stomach pain, or signs of a medical emergency such as a serious allergic reaction or severe digestive problems, seek immediate help. These could be signs of more severe complications, such as an intestinal blockage or inflammation of the pancreas (pancreatitis), which require prompt medical intervention.

Although reports of Mounjaro are often positive, especially in aiding weight loss, side effects are expected. Be sure to monitor your body and how you are feeling and report any side effects. This gives your medical provider a full picture of what’s going on in your body and can make sure they are able to support you best on your journey.

a blue plate with the words weight loss in the centre

Other Side Effects to Watch Out For

Besides constipation, Mounjaro has a range of other potential side effects that are worth mentioning. The most common Mounjaro side effects include nausea, diarrhoea, vomiting, and abdominal pain. However, there are more serious side effects to be aware of. According to the boxed warning—the most serious warning issued by the FDA—Mounjaro carries a potential risk of thyroid tumours and thyroid cancer, which has been observed in animal studies. Although the increased risk of thyroid cancer in humans has not been conclusively proven, it is essential to be vigilant for symptoms such as a lump in the neck, hoarseness, or difficulty swallowing. 

Beyond thyroid concerns, it’s worth noting that Mounjaro has been linked to gallbladder problems, kidney problems, and even kidney failure in rare cases. If you experience symptoms like yellowing of the skin or eyes, dark urine, or unusual tiredness, these could all be signs of serious side effects and warrant immediate medical evaluation.

Green injection How long does Ozempic stay in your system?

So, Who Should Avoid Mounjaro?

Like all drugs, Mounjaro isn’t suitable for everyone, and that is another reason this medication should only ever be taken under the supervision of registered healthcare professionals. For example, people with a history of medullary thyroid carcinoma or those with Multiple Endocrine Neoplasia syndrome type 2 (a rare endocrine disorder) should avoid using this medication due to the potential risk of thyroid cancer. However, this list is not exclusive, and other health complications may make it unsuitable. 

Mounjaro and Drug Interactions: What You Need to Know

If you are already taking any medication, then it is essential to consider potential drug interactions. For example, Mounjaro may interact with other diabetes medications, which can increase the risk of symptoms of low blood sugar (hypoglycemia). If you’re on multiple diabetes medicines, your doctor may need to adjust your treatment plan to ensure safe and effective use. Before taking any new treatment, check with your health provider to ensure it can be taken alongside Mounjaro safely. 

A collection of pills

Weighing the Pros and Cons: Is Mounjaro Right for You?

We’ve already elaborated on the fact that Mounjaro isn’t suitable for everyone. Deciding whether Mounjaro is right for you involves weighing the potential benefits against the possible risks and side effects and how all of this fits into your own lifestyle. For many, the prospect of significant weight loss and improved blood sugar control is worth the trade-offs. However, understanding the full range of Mounjaro’s side effects, including the less talked about ones like constipation, can help you make a more informed decision and make sure you know exactly what you are getting into.

Remember, no two weight loss journeys are the same, and what works for one person might not work for another – and that’s okay. You can carve your own unique path with a multitude of options out there, and you will be sure to find exactly what works for you. If you are considering Mounjaro or any other type of weight loss medication, make your first port of call by speaking with a medical professional who is well-versed in these types of drugs. Make a list in advance of any questions and ask about alternatives. 

feet on a weighing scale

In Conclusion

While Mounjaro constipation can be an unwelcome side effect it is a common complaint. Understanding how to manage it effectively can make all the difference and prevent it from turning into something more serious. Staying hydrated and eating the right diet can help manage these symptoms and make sure Mounjaro constipation doesn’t create too much of an impact on your lifestyle. By monitoring any potential side effects and working closely with your healthcare provider, you can make the best choices for your health and well-being on an ongoing basis. You may find that once you start this medication, it is no longer suitable and look to switch to something else.

Have you tried MounjaroExperienced Mounjaro constipation? What are your tips and tricks for managing it?

If you are on a weight loss journey and want further support and company, then join my free Facebook Group here. Oh, and if you have found this website and articles useful and you’d like to know how you can say thank you, then I am always appreciative of receiving a virtual coffee here.


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About-me-soph-obsessedMore From Me

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Navigating the complex world of weight loss can feel like a full-time job. For many years, weight loss has consumed me, and I have struggled to find something that fits. I recently wrote about the weight loss drug Mounjaro, which is reported to help people who have struggled with weight loss in the past. Today, I wanted to touch on a common complaint users have reported: Mounjaro constipation. If you've been asking yourself, "Does Mounjaro cause constipation?" or are just curious about its side effects in general, then this post is for you!

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